Triptorelin
GnRH agonist for prostate cancer.
What it is
Triptorelin (Trelstar) is a synthetic GnRH agonist FDA-approved for advanced prostate cancer. It is structurally similar to leuprolide and produces equivalent clinical effects through GnRH receptor desensitization and downregulation.
Mechanism of action
Same as leuprolide — initial gonadotropin flare followed by sustained suppression of LH/FSH release and consequent suppression of gonadal sex hormone production.
Approved indications
Advanced prostate cancer requiring medical castration. Used outside the US for additional indications including endometriosis and breast cancer.
Why this is out of scope at The Tide
Specialty oncology medication appropriately prescribed and managed by urologic oncology or medical oncology with appropriate experience in prostate cancer hormone therapy. The Tide does not provide oncology care.
Where to learn more
Urologic oncology or medical oncology.
From the same category.
Histrelin
Vantas · Supprelin LA
GnRH agonist implant for central precocious puberty and prostate cancer.