Acetyl tetrapeptide-3
Hair follicle peptide for hair density.
What it is
Acetyl tetrapeptide-3 is a cosmetic peptide commonly found in topical hair density products, often combined with red clover extract in formulations marketed under names including Capixyl. It is positioned as a topical alternative to medical hair loss treatments.
Mechanism of action
Hypothesized effects on hair follicle biology, including extension of the anagen (growth) phase of the hair cycle and support of dermal papilla cell function. Topical application is intended to support hair density and reduce shedding.
Use as cosmetic ingredient
Formulated into topical hair products at various concentrations. Available through cosmetic and aesthetic retail channels.
Why this is out of scope at The Tide
Hair loss is appropriately evaluated and managed by dermatology, particularly when there is concern about underlying medical conditions or when patients want evidence-based interventions. Established treatments (minoxidil, finasteride, oral minoxidil) have substantially stronger evidence than cosmetic peptides for most hair loss patterns.
The Tide does not provide hair loss treatment or recommend specific topical hair products.
Where to learn more
Dermatology providers, particularly those with specific expertise in hair disorders.