NAD+ in Houston, with the honesty it actually deserves.
NAD+ by IV or subcutaneous injection, with honest guidance on what is and isn't known. Compounded NAD+ is not FDA-approved for these uses.
A coenzyme central to every cell’s energy production.
Nicotinamide adenine dinucleotide — NAD+ — is a coenzyme present in every living cell. It’s required for mitochondrial energy production, DNA repair signaling, sirtuin enzyme function, and cellular redox balance. NAD+ levels decline with age; what that means for health in people is still being studied.
That’s the established biology. What’s less established is how reliably raising NAD+ via IV or subcutaneous administration translates into the outcomes people walk in asking about — energy, focus, recovery, longevity. Most of the rigorous human RCT data is on oral precursors (NMN and NR), and those results are mixed. Evidence for intravenous and subcutaneous NAD+ in people is limited, and NAD+ is not FDA-approved for these uses.
NAD+ for injection or infusion is compounded by licensed pharmacies. Compounded preparations are not FDA-approved. Read more about how compounding is regulated.
What’s known about NAD+ — and where the evidence is limited.
NAD+ therapy sits at an unusual place in medicine: the underlying biology is well-characterized, but the formal trial base for IV and subcutaneous delivery is thinner than the marketing implies. Here’s how we think about it — and what we tell every patient before their first infusion.
Mechanism & cellular biology
NAD+ is essential for mitochondrial ATP production, sirtuin activation (which regulates metabolism, inflammation, and DNA repair), and PARP-mediated DNA repair. NAD+ declines with age. Restoring NAD+ in cells, in animal models, has reproducible effects on these pathways.
Confidence: High · Established biologyEnergy, focus, and recovery claims
These are the outcomes most clinics market. Benefit for energy, cognition, or recovery from IV or subcutaneous NAD+ has not been established in rigorous human trials, and we don’t claim it.
Confidence: Low · Not established in peopleAnti-aging & longevity claims
You’ll see NAD+ marketed as a longevity intervention. The 2026 PRISMA review of NAD-augmenting therapies found no eligible intervention studies evaluating intravenous, intramuscular, or subcutaneous NAD+ for anti-aging or wellness outcomes. We don’t position NAD+ as a longevity treatment. We don’t claim specific benefits; we discuss the limited evidence so you can make an informed decision.
Confidence: Low · Marketed beyond the evidence baseFoundations come first.
Sleep, physical activity, nutrition, and stress regulation come before any infusion. We’re honest about that up front.
NAD+ is not a fix for what’s broken.
If sleep is poor, activity is inconsistent, or stress is chronically high, those come first. Otherwise we’re charging you to mask a problem.
- Sleep — the foundation nothing replaces
- Regular physical activity and nutrition
- Stress regulation and sleep habits
- An honest conversation about whether NAD+ is the right next step
From consultation to first infusion, in real medicine.
NAD+ administration looks different from a typical “IV bar” protocol. Slow infusion, focused workup, defined series, honest reassessment — not a recurring monthly membership.
Initial consultation
In person at our Houston clinic. We discuss what you’re hoping NAD+ will address, talk honestly about what’s evidence-supported and what’s not, and decide together whether an initial series makes sense — or whether something more fundamental should come first.
Focused baseline panel
A focused baseline panel rather than a full hormone workup — metabolic panel, CBC, inflammatory markers, and any indication-specific labs relevant to your picture. We’re not screening for deficiency; we’re confirming you’re appropriate for the protocol and have no contraindications.
First infusion or injection
IV NAD+ runs slowly — typically 60–120 minutes for the first session, sometimes longer. Fast infusion causes flushing, nausea, and chest tightness; slower infusion reduces these reactions. Subcutaneous injection is an alternative for patients who want to self-administer between sessions or who don’t tolerate IV well.
Defined plan
If NAD+ is chosen, your provider defines a limited plan upfront so you know what you’re committing to, and we reassess regularly rather than continuing to bill.
Honest reassessment
After the initial series, we reassess: did it work, was it worth the cost, what comes next? Some patients discontinue. Others move on to a different intervention. We don’t push recurring membership — we recommend what fits.
Ready to start the conversation?
A 45-minute consultation with one of our providers. We’ll discuss what you’re hoping NAD+ will do, what the evidence does and doesn’t support, and decide together whether it fits — or whether something else makes more sense for what you’re working on.
What NAD+ can — and can’t — do.
The biology is real. The marketing is often ahead of the trial data. Here’s the honest version of what to expect.
What to know going in
- NAD+ by IV or injection is compounded and not FDA-approved for energy, focus, recovery, or aging
- Benefits in people have not been established in rigorous trials
- Slow infusion reduces common infusion reactions
- Any plan is defined and time-limited — not a recurring monthly membership
What it can’t do
- Replace sleep, physical activity, nutrition, or stress management
- Deliver “anti-aging” or “longevity” outcomes in any way the formal trial data supports
- Be promised to produce any specific effect
- Be administered safely as a fast IV push — slow infusion is non-negotiable
- Be appropriate for patients with severe liver or kidney disease, active malignancy, or pregnancy without specific consultation
- Be cheap — the cost is real, and we’ll be honest if we don’t think it’s worth it for your situation
This page describes a compounded peptide or off-label medication. The compound is not FDA-approved for the proposed indications. Available human clinical evidence is limited. Information on this page is provided for educational purposes; clinical decisions are made individually during provider consultation. See our full disclaimers for additional context.
Before you book.
How much does NAD+ therapy cost in Houston?
Consultations start at $49 (see pricing). NAD+ pricing depends on the plan your provider recommends. We define any plan upfront so you know the total commitment before starting. We discuss specifics during consultation, with no surprises.
What’s the difference between IV NAD+ and oral NMN or NR?
Oral NMN and NR are NAD+ precursors — your body converts them into NAD+. Most of the rigorous human RCT data on NAD+ augmentation is on these oral precursors, with mixed results across endpoints. IV and subcutaneous NAD+ deliver the molecule directly, bypassing first-pass metabolism. The formal trial data for IV/SC is limited. They’re different interventions answering different questions, and we’ll discuss which (if either) fits your situation.
Why do you only offer IV and subcutaneous? Why not oral NMN/NR?
Oral NAD+ precursors are widely available as supplements at retail. They don’t need a clinic. If you want to try oral NMN or NR, we’re happy to discuss the evidence and what to look for in a quality product — but we don’t sell them. We focus on what requires physician oversight: IV infusion (which can cause adverse reactions if administered improperly) and subcutaneous compounded NAD+ (which requires a prescription).
Why does the IV take so long?
Fast IV NAD+ causes flushing, nausea, chest tightness, and a generally unpleasant experience. Slow infusion — 60–120 minutes for a typical dose, sometimes longer — eliminates most of those reactions. The clinics that push you through in 30 minutes are not delivering a better experience; they’re delivering a less tolerable one. The infusion time is part of the protocol, not an inconvenience to optimize away.
Are there side effects?
The most common reactions during infusion are mild flushing, transient nausea, and pressure or tightness in the chest — typically managed by slowing the drip rate. Reactions are generally fewer with slow administration. Serious adverse events are rare in available data. We discuss specific contraindications during consultation — patients with active malignancy, severe liver or kidney disease, or who are pregnant generally aren’t candidates.
How is this different from the IV bar across the street?
An IV bar typically delivers a fixed-protocol infusion as a wellness experience, often without physician oversight. We deliver NAD+ as a clinical intervention — physician-supervised, defined series, focused baseline labs, honest reassessment about whether to continue. The medication is often the same. The medical model isn’t.
Do you accept insurance?
NAD+ therapy is not typically covered by insurance because it’s a compounded preparation that is not FDA-approved for these uses. Some patients use HSA/FSA funds for consultations and certain costs. We don’t bill insurers directly. We can provide receipts suitable for HSA/FSA submission.
Start with a conversation, not an infusion.
A 45-minute consultation with one of our Houston providers. We’ll discuss what is and isn’t known about NAD+, and decide together whether it fits.