NAD+ in Houston, with the honesty it actually deserves.
Sharper focus, faster recovery, and the energy you remember having — delivered as IV or subcutaneous injection, with honest guidance on what NAD+ does well and where the evidence is still catching up.
A coenzyme central to every cell’s energy production.
Nicotinamide adenine dinucleotide — NAD+ — is a coenzyme present in every living cell. It’s required for mitochondrial energy production, DNA repair signaling, sirtuin enzyme function, and cellular redox balance. NAD+ levels decline with age, and that decline correlates with the same biological processes that drive fatigue, slower recovery, and reduced cognitive sharpness.
That’s the established biology. What’s less established is how reliably raising NAD+ via IV or subcutaneous administration translates into the outcomes people walk in asking about — energy, focus, recovery, longevity. Most of the rigorous human RCT data is on oral precursors (NMN and NR), and those results are mixed. Direct intravenous and subcutaneous NAD+ has been used clinically for years and patients frequently report meaningful effects, but the formal trial base for those routes is limited.
NAD+ is a compounded medication prepared by licensed compounding pharmacies under specific regulatory frameworks. We work only with licensed compounding partners that meet documented quality standards.
What NAD+ does well — and where the evidence is still catching up.
NAD+ therapy sits at an unusual place in medicine: the underlying biology is well-characterized, the clinical experience is real, and the formal trial base for IV and subcutaneous delivery is thinner than the marketing implies. Here’s how we think about it — and what we tell every patient before their first infusion.
Mechanism & cellular biology
NAD+ is essential for mitochondrial ATP production, sirtuin activation (which regulates metabolism, inflammation, and DNA repair), and PARP-mediated DNA repair. NAD+ declines with age. Restoring NAD+ in cells, in animal models, has reproducible effects on these pathways.
Confidence: High · Established biologyCognitive sharpness, energy, recovery
The most consistent patient-reported effects we see clinically: improved focus during the infusion and for days after, better workout recovery, and a sense of mental clarity. These reports are real and consistent — but they’re patient experience, not endpoint data from large RCTs. Treat them as encouraging, not definitive.
Confidence: Moderate · Strong clinical signal, limited trial dataAnti-aging & longevity claims
You’ll see NAD+ marketed as a longevity intervention. The 2026 PRISMA review of NAD-augmenting therapies found no eligible intervention studies evaluating intravenous, intramuscular, or subcutaneous NAD+ for anti-aging or wellness outcomes. We don’t position NAD+ as a longevity treatment. We position it as a clinical intervention with specific, near-term benefits worth the cost for the right patient.
Confidence: Low · Marketed beyond the evidence baseNAD+ extends the ceiling. Foundations are the floor.
NAD+ tends to deliver the most for patients who already have solid foundations — sleep, training, recovery, stress regulation. We’re honest about that distinction up front, because the people who benefit most are the ones already doing the underlying work.
NAD+ extends what’s already working. It doesn’t fix what’s broken.
NAD+ may be appropriate as a layer on top of solid foundations — where the question is “how do I extend what’s already working” rather than “what fixes what’s broken.” If sleep is broken, training is inconsistent, or stress is chronically high, those come first. Otherwise we’re charging you to mask a problem.
- Sleep — the biggest natural NAD+ driver, and the one nothing replaces
- Resistance training and aerobic capacity — both raise NAD+ on their own
- Stress regulation and recovery practices stack with NAD+ effects
- An honest conversation about whether NAD+ is the right next step
From consultation to first infusion, in real medicine.
NAD+ administration looks different from a typical “IV bar” protocol. Slow infusion, focused workup, defined series, honest reassessment — not a recurring monthly membership.
Initial consultation
In person at our Houston clinic. We discuss what you’re hoping NAD+ will address, talk honestly about what’s evidence-supported and what’s not, and decide together whether an initial series makes sense — or whether something more fundamental should come first.
Focused baseline panel
A focused baseline panel rather than a full hormone workup — metabolic panel, CBC, inflammatory markers, and any indication-specific labs relevant to your picture. We’re not screening for deficiency; we’re confirming you’re appropriate for the protocol and have no contraindications.
First infusion or injection
IV NAD+ runs slowly — typically 60–120 minutes for the first session, sometimes longer. Fast infusion causes flushing, nausea, and chest tightness; slow infusion is well-tolerated. Subcutaneous injection is an alternative for patients who want to self-administer between sessions or who don’t tolerate IV well.
Defined cycle
A typical initial series is 5–10 sessions over several weeks, depending on the indication and your response. We define the series upfront so you know what you’re committing to. Most patients report effects starting around session 2–3; if there’s no meaningful response by session 5, we have an honest conversation rather than continuing to bill.
Honest reassessment
After the initial series, we reassess: did it work, was it worth the cost, what comes next? Some patients do periodic maintenance (monthly or quarterly). Others discontinue. Others move on to a different intervention. We don’t push recurring membership — we recommend what fits.
Ready to start the conversation?
A 45-minute consultation with one of our physicians. We’ll discuss what you’re hoping NAD+ will do, what the evidence does and doesn’t support, and decide together whether it fits — or whether something else makes more sense for what you’re working on.
What NAD+ can — and can’t — do.
The biology is real. The clinical experience is real. The marketing is often ahead of the trial data. Here’s the honest version of what to expect.
What NAD+ may help with
- Improved focus and mental clarity, often noticeable during and shortly after infusion
- Better-feeling recovery from training, hard work, or jet lag in many patients
- A real, patient-reported sense of energy and engagement that lasts days to weeks for responders
- Adjunctive support for cellular biology in patients with high cognitive or physical demands
- Reasonable safety profile when administered as slow infusion under physician oversight
- Defined, time-limited initial series — not a recurring monthly membership
What it can’t do
- Replace sleep, training, nutrition, or stress management — these all raise NAD+ on their own
- Deliver “anti-aging” or “longevity” outcomes in any way the formal trial data supports
- Work for everyone — response rates appear to be variable, with some patients reporting no meaningful effect
- Be administered safely as a fast IV push — slow infusion is non-negotiable
- Be appropriate for patients with severe liver or kidney disease, active malignancy, or pregnancy without specific consultation
- Be cheap — the cost is real, and we’ll be honest if we don’t think it’s worth it for your situation
Before you book.
How much does NAD+ therapy cost in Houston?
The initial consultation is $349. Individual NAD+ infusion sessions and subcutaneous protocols vary based on dose and duration — typical range is $250–$600 per session for IV, lower for subcutaneous. We define the initial series upfront so you know the total commitment before starting. We discuss specifics during consultation, with no surprises.
What’s the difference between IV NAD+ and oral NMN or NR?
Oral NMN and NR are NAD+ precursors — your body converts them into NAD+. Most of the rigorous human RCT data on NAD+ augmentation is on these oral precursors, with mixed results across endpoints. IV and subcutaneous NAD+ deliver the molecule directly, bypassing first-pass metabolism. The clinical experience with IV/SC is robust; the formal trial data is thinner. They’re different interventions answering different questions, and we’ll discuss which (if either) fits your situation.
Why do you only offer IV and subcutaneous? Why not oral NMN/NR?
Oral NAD+ precursors are widely available as supplements at retail. They don’t need a clinic. If you want to try oral NMN or NR, we’re happy to discuss the evidence and what to look for in a quality product — but we don’t sell them. We focus on what requires physician oversight: IV infusion (which can cause adverse reactions if administered improperly) and subcutaneous compounded NAD+ (which requires a prescription).
Why does the IV take so long?
Fast IV NAD+ causes flushing, nausea, chest tightness, and a generally unpleasant experience. Slow infusion — 60–120 minutes for a typical dose, sometimes longer — eliminates most of those reactions. The clinics that push you through in 30 minutes are not delivering a better experience; they’re delivering a less tolerable one. The infusion time is part of the protocol, not an inconvenience to optimize away.
Are there side effects?
The most common reactions during infusion are mild flushing, transient nausea, and pressure or tightness in the chest — typically managed by slowing the drip rate. Most patients tolerate the protocol well when administered slowly. Serious adverse events are rare in available data. We discuss specific contraindications during consultation — patients with active malignancy, severe liver or kidney disease, or who are pregnant generally aren’t candidates.
How is this different from the IV bar across the street?
An IV bar typically delivers a fixed-protocol infusion as a wellness experience, often without physician oversight. We deliver NAD+ as a clinical intervention — physician-supervised, defined series, focused baseline labs, honest reassessment about whether to continue. The medication is often the same. The medical model isn’t.
Do you accept insurance?
NAD+ therapy is not typically covered by insurance because it’s a compounded medication used off-label. Some patients use HSA/FSA funds for consultations and certain costs. We don’t bill insurers directly. We can provide receipts suitable for HSA/FSA submission.
Start with a conversation, not an infusion.
A 45-minute consultation with one of our Houston physicians. We’ll discuss what NAD+ does well, where the evidence is still catching up, and decide together whether it fits.